FAQ

Hyaluronic acid is injected directly into the tissue comprising the vulvovaginal area. The product can thus contribute efficiently to hydrating this tissue.

Cellar activity is stimulated as a result. In this way, the production of collagen and elastin fibres is boosted, and this also helps improve the quality of the vulvovaginal mucosa¹.

¹Quan T et al,: Enhancing structural support of the dermal microenvironment activates fibroblasts, endothelial cells, and keratinocytes in aged human skin in vivo. J Invest Dermatol. 2013 Mar; 133(3):658-67.

Like all other organs of the body, the female genitalia are not immune to the passage of time, particularly during menopause. The tissues in the vulvar region are particularly sensitive to oestrogen production decreases.

Without oestrogen, the vaginal mucosa becomes thinner, dryer and more fragile. The vagina loses its elasticity and flexibility. The natural protection of the vagina is less efficient. The risk of vaginal infections increases.² The discomfort caused by these physiological changes can affect the quality of women’s daily lives.

These problems occur more often during menopause.² They can also occur in patients of childbearing age.

²Mac Bride MB et al, : Vulvovaginal atrophy. Mayo Clin Proc. 2010 Jan; 85(1):87-94

DESIRIAL® and/or DESIRIAL® PLUS injections are administered in a medical facility by a legally authorised physician, specialised in reconstructive and functional gynaecology, who has sound anatomical knowledge of the treatment site and is experienced in filler product injection techniques.

A local anaesthetic may be used before each injection of DESIRIAL® and/or DESIRIAL® PLUS to ensure a more comfortable and effective treatment.


DESIRIAL® injections are generally administered in the vulva and the vaginal entrance. Your physician will insert a needle superficially to deposit the product, just below the mucosa to be rehydrated.

Your physician will inject DESIRIAL® PLUS just under the dermis of the labia majora. For this, he/she will use a cannula so to deposit the product along the length of the labia majora, without any risk of injury. The procedure takes approximately 20 minutes.

The average expected effect for this type of product is 6 to 12 months. This period may be shorter or longer depending on the profile of the treated areas, the quantities injected, the injection technique used and your lifestyle. A top-up procedure a few weeks after the initial injections can extend and optimise the results. It is advisable not to inject more than 20 ml of cross-linked hyaluronic acid per person/per year.

Your physician will be able to advise you on the DESIRIAL® product that is best suited to your needs. Ask your doctor for information about products in the DESIRIAL® range and make an appointment to start your personalised treatment.

Avoid humid places such as swimming pools, gyms, steam rooms, hot tubs, etc. for 10 days.

Avoid sexual intercourse for 5 days.

Avoid activities that are likely to exert pressure on the treated area for several days (biking, horseback riding, etc.).

If you are pregnant or breast feeding.

If you have areas showing clinical signs of inflammation and/or viral infection (e.g.: papilloma, herpes), bacterial infection or fungal infection (e.g.: mycosis) and/or are currently under treatment for these pathologies.

If you have known hypersensitivity to any of the components (e.g.: hyaluronic acid or mannitol). Remember to tell your doctor about your medical history, including any auto-immune diseases or current treatments.

If you have hypertrophic scarring.

The information contained herein is not exhaustive. A consultation with your doctor prior to the injection of a DESIRIAL® range product is essential to determine whether these products are suited for you.

Although rare, there may be side effects after the injection and/or in a delayed manner, including:

• Inflammatory reactions such as redness or swelling, potentially associated with itching and/or pain, especially with pressure. These reactions may last for several days.
• Bleeding, tightening of the skin or a change in skin colour (staining or discolouration) in the injected areas.
• Infection (DESIRIAL® PLUS only).
• Local mobility of the gel (for injection with DESIRIAL® PLUS).
• Hematoma
• Rare cases of granuloma abscess necrosis and hypersensitivity
• Difficulty in urination (DESIRIAL® only)
• Post-injection pain (DESIRIAL® PLUS only)

Also, if you have previously had genital herpes, there is a risk that the needle punctures could cause a new outbreak. The persistence of any of the above adverse effects beyond one week or the occurrence of any other adverse effect should be reported to the practitioner as soon as possible. These side effects may require treatment and could take for several months to resolve (for the injection with DESIRIAL® PLUS). Consult your doctor.