What treatments are available?

Traditional methods aim to compensate for the lack of oestrogen with medication. But these local treatments applied on the weakened tissues can be difficult to cope with daily and are not sufficient to rehydrate the vagina locally.


A more recent treatment consists of injecting DESIRIAL® hyaluronic acid gel directly into the vestibular and vaginal mucosa to rehydrate and tone it. The beneficial effects of this treatment may last up to 12 months4.



A molecule that is naturally present in the human body, hyaluronic acid is found in certain types of tissue such as the skin and mucous membranes. It rehydrates your vaginal mucosa.1


It has the capacity to hold up to 1,000 its weight in water,2 thereby playing a key role in the hydration and toning of the tissues that contain it.3

Hyaluronic acid can be transformed into an injectable gel to treat women affected by vulvovaginal atrophy. Given its short life cycle and water solubility, the molecule must be stabilised using a cross-linking process.


This specific cross-linking process extends the life cycle of the gel injected into the tissues of the body. Each of VIVACY’s injectable gels is designed to adapt to the areas for which it is intended.


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1Fakhari, A. & al. “Applications and Emerging Trends of Hyaluronic Acid in Tissue Engineering, as a Dermal Filler, and in Osteoarthritis Treatment”. Acta Biomater.; 9(7): 7081–7092, 2013.

2Meschino, J._Encapsulated Hyaluronic Acid: An Essential Nutrient for Ageless Skin and the Reversal of Wrinkles. In: Meschino, J. Wrinkle-Free Zone: Your Guide to Perfect Skin in 30 Days. ReadHowYouWant ed. 2012; 43-49.
3Stern, R. Maibach, HI. Hyaluronan in skin: aspects of aging and its pharmacologic modulation. Clin Dermatol. 2008; 26(2): 106-122.

4Open, non-interventional post-market, follow-up study assessing the efficacy and tolerance of DESIRIAL® PLUS in its intended use scenario. Study report (RA1600501): analysis with 35 injected patients, possibly with top-ups. Immediate volume increase effect assessed by the physician on a scale of 1 (very low) to 10 (very good). Average grade of 9.3 just after injecting the product. Atrophy assessed by the physician on a scale of 1 (no atrophy) to 4 (severe). Statistically significant decrease in grade after 6 months compared to the grade before injection (average grade of 2.7 before injection and 1.4 after 6 months; p<0.001).